April bought Splinter an antique Japanese scepter at a sale, along with other gifts for her turtle friends. As it turned out, this scepter was not just an ordinary antique, but a prototype of a time machine. However, it only works when the weight of the time travelers is the same on both sides.
As it happened, the scepter transported April to feudal Japan in 1603. The turtles followed her, but instead of ending up in the temple where the scepter was supposed to be, they found themselves in the middle of a battlefield. In all this confusion, Michelangelo is lost with the scepter. Now the turtles must not only save April, but also return the scepter. In our time, things are not boring at all either.

Abbott and Costello meet Bruce and Vicky in London, who are about to get married. It turns out that Henry Jekyll, the guardian of the girl, does not approve of her choice and using his dark alter ego in the person of Mr. Hyde tries to destroy Bruce and at the same time the two main characters.

Lou Francis and Bud Alexander are aspiring private investigators fresh out of specialty school. Boxer Tommy Nelson becomes their first client. He has escaped from prison, where he was imprisoned on false charges of murdering his manager. Nelson asks his buddies to escort him to his fiancée, Helen. The thing is that her uncle, Dr. Philip Gray, has invented an "invisibility serum", which the boxer wants to inject himself to use the invisibility to find the real killer and prove his innocence.