In the 2000s, Pat Calhoun and his girlfriend were members of a radical left-wing extremist group, and when a murder occurred during one of their raids, his comrades were forced to flee separately. Sixteen years later, the man lives in Southern California under the name Bob Ferguson and is raising his teenage daughter, whom he forbids from even having a cell phone due to his constant paranoia. Bob's fears prove to be well-founded when his old enemy, Colonel Lockjo, begins hunting him and his daughter.

Elphaba is now known as the Wicked Witch of the West and lives in exile in the forests of Oz. She continues to fight for the rights of animals whose voices are suppressed and tries to reveal the truth about the Wizard. The Good Witch Glinda becomes a public symbol of goodness, lives in the Emerald City palace, and enjoys the benefits of her popularity. At the behest of Madame Morrible, she addresses the people of Oz, assuring them of stability under the Wizard's rule. As Glinda's fame grows and she prepares for her wedding to Prince Fiero, the sorceress begins to worry about her broken relationship with Elphaba. Glinda's attempts to reconcile Elphaba with the Wizard are unsuccessful, which only deepens their conflict.